downers
n.
镇定剂，令人沮丧的人( downer的名词复数 );
例句:
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She was taking uppers and downers at the time.
她那时在服用兴奋剂和抑制剂。
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Now it's too late - I'm on a 1000 downers now, I'm drowsy.
但现在一切都晚了,我吃了1000片镇定药.
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They became known as downers as they were often used to ease down from tripping or speeding.
来自BBC